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Case Report
 
Colobomatous cyst: Histopathological characterization
Abdullah Al-Khamiss1, Ayman Ayoubi2, Muhammad Manzoor3, Sadeq Al-Dandan1
1Department of Pathology, King Fahad Medical City, Riyadh, Saudi Arabia.
2Department of Ophthalmology, King Fahad Medical City, Riyadh, Saudi Arabia.
3Department of Radiology, King Fahad Medical City, Riyadh, Saudi Arabia.

Article ID: 100003Z11AA2015
doi:10.5348/Z11-2015-3-CR-3

Address correspondence to:
Abdullah Saleh Al-Khamiss
Department of Pathology, King Fahad Medical City
Al-Olaya, Khurais road, Riyadh city, Riyadh region
Kingdom of Saudi Arabia
Phone: 00966-506-13-9201

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How to cite this article:
Al-Khamiss A, Ayoubi A, Manzoor M, Al-Dandan S. Colobomatous cyst: Histopathological characterization. J Case Rep Images Pathol 2015;1:12–16.


Abstract
Introduction: Colobomatous cyst is one of the rare orbital cystic lesions that have wide range of differential diagnosis. It is a congenital lesion that can be easily misdiagnosed as malignant tumor, leading to exposing the patient to unnecessarily overtreatment.
Case Report: This is a rare case of congenital colobomatous cyst in an infant girl. The cyst was associated with a microphthalmic globe. Radiologically, the cyst was located in the inferior half of the orbital cavity. Surgical excision was performed and the histopathological examination demonstrated a collapsed cyst with smooth tan lining. The wall of the cyst had an inner neuroretinal layer and an outer fibrovascular layer.
Conclusion: Any orbital cystic lesion should not be diagnosed without the clinicopathological and radiopathological correlations, to avoid any histopathological over diagnosis of some benign cysts as a malignant one. The pathologic features of colobomatous cysts are rarely described in literature with only one article in the PubMed search discussing these features in some details.

Keywords: Childhood, Colobomatous cyst, Histopathology, Infant, Microphthalmic globe, Orbital cystic lesions


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Author Contributions
Abdullah Al-Khamiss – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Ayman Ayoubi – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Muhammad Manzoor – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Sadeq Al-Dandan – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2015 Abdullah Al-Khamiss et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.