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Case Report
 
Olmesartan induced gastroenteropathy and acute kidney injury: A case report and review of literature
Vani Thirumala1, Miller Timothy2, Seshadri Thirumala3
1BSA Neurosciences, Pre Med Student, UT Austin, Texas, USA
2MD Gastroenterology, LDDA, Lubbock Texas, USA
3MD Surgical Pathology, Ameripath Lubbock, Texas, USA

Article ID: 100019Z11VT2018
doi: 10.5348/100019Z11VT2018CR

Corresponding Author:
Seshadri Thirumala, MD,
1912 Aberdeen Ave,
Lubbock, Texas 79407, USA

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How to cite this article
Thirumala V, Timothy M, Thirumala S. Olmesartan induced gastroenteropathy and acute kidney injury: A case report and review of literature. J Case Rep Images Pathol 2018;4:100019Z11VT2018.


ABSTRACT

Olmesartan, an Angiotensin-Receptor blocker (ARB) has been widely reported as causing severe enteropathy. We present a case of Acute Kidney Injury (AKI) secondary to severe diarrhea induced by Olmesartan therapy in a 58-year-old patient. Acute kidney injury (AKI) is an abrupt and usually reversible decline in the glomerular filtration rate (GFR). This results in an elevation of serum blood urea nitrogen (BUN), creatinine, and other metabolic waste products that are normally excreted by the kidney. Clinical presentation of acute kidney injury in patients on Olmesartan can be misleading and delay accurate diagnosis and treatment.

Keywords: Acute kidney injury, Angiotensin converting enzyme, Angitotensin receptor blocker, Enteropathy, Olmesartan, Sprue


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Author Contributions
Vani Thirumala – Substantial contributions to conception and design, Acquisition of data, Analysis and Interpretation of data, Drafting of the article, Revising it critically for important intellectual content, Final approval of the version to be published
Miller Timothy – Substantial contributions to conception and design, Acquisition of data, Analysis and Interpretation of data, Drafting of the article, Revising it critically for important intellectual content, Final approval of the version to be published
Seshadri Thirumala – Substantial contributions to conception and design, Acquisition of data, Analysis and Interpretation of data, Drafting of the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of Submission
The corresponding author is the guarantor of submission.
Source of Support
None
Consent Statement
Written informed consent was obtained from the patient for publication of this study.
Conflict of Interest
Author declares no conflict of interest.
Copyright
© 2018 Vani Thirumala et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.