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Case Report
Adenocarcinoma in Barrett’s esophagus cytologically diagnosed through fluid biopsy using the endogastric capsule: A case report
1 MD, Surgical Pathologist and Oncologist, Retired, Previously Director of Department of Surgical Pathology, Ospedale San Salvatore, Pesaro, Italy
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Pietro Muretto
MD, Surgical Pathologist and Oncologist, Department of Surgical Pathology, Ospedale San Salvatore, Pesaro,
Italy
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Article ID: 100034Z11PM2020
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Muretto P. Adenocarcinoma in Barrett’s esophagus cytologically diagnosed through fluid biopsy using the endogastric capsule: A case report. J Case Rep Images Pathol 2020;6:100034Z11PM2020.ABSTRACT
Intramucosal adenocarcinoma in Barrett’s esophagus is described in a 63-year-old man who from 30 years experienced symptoms such as nocturnal acid reflux with heartburn, sourness, and burning sensation in the back of the throat. One year ago he come to medical consultation and accepted to be submitted to cytologic analyses of fluid samples drawn through the endogastric capsule. Microscopy showed many stratified esophagus cells with several nests of neoplastic nucleolated cells. He was submitted to endoscopy with some biopsies in Barrett’s disease tract (3.5 cm on length). Histology showed frequent intestinalized columnar epithelium together with intramucosal adenocarcinoma. The patient was submitted to surgery with removal of 5 cm of esophagus together with the gastric cardiac area. The definitive histological analyses confirmed the diagnosis of intramucosal adenocarcinoma of 5 mm in diameter in Barrett’s esophagus.
Keywords: Adenocarcinoma in Barrett’s esophagus, Cytologic diagnosis by fluid biopsy, Endogastric capsule
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Author Contributions
Pietro Muretto - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthor declares no conflict of interest.
Copyright© 2020 Pietro Muretto. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
