Case Report


Green neutrophilic inclusions and a novel association with gangrenous ischemic colitis

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1 Medical Student, Burrell College of Osteopathic Medicine, Las Cruces, New Mexico, United States

2 Medical Laboratory Technician, Mountainview Regional Medical Center, Las Cruces, New Mexico, United States

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Mason Marshall

435 Ithaca Ct. Apt. J5, Las Cruces, New Mexico 88011,

United States

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Article ID: 100041Z11MM2020

doi: 10.5348/100041Z11MM2020CR

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How to cite this article

Marshall M, Rios I. Green neutrophilic inclusions and a novel association with gangrenous ischemic colitis. J Case Rep Images Pathol 2020;6:100041Z11MM2020.

ABSTRACT


Blue–green refractile neutrophilic inclusions on peripheral smears are a rare and critical finding. Finding of these inclusions has typically been associated with a poor short-term prognosis causing them to be dubbed, “Green crystals of death.” Early reports have suggested a link to acute hepatic failure as the prevailing etiology during which these inclusions appear. Here, we present a case of a 75-year-old male who presented with ischemic colitis in which blue–green neutrophilic inclusions were discovered on peripheral smears. This is the first documented case of ischemic colitis associated with the appearance of green intracytoplasmic inclusions in neutrophils.

Keywords: Green crystals, Ischemic colitis, Neutrophilic inclusions

SUPPORTING INFORMATION


Acknowledgments

The authors would like to thank Dr. Sanjay Lahiri for his guidance with the publication process and Randy Aguilera for his assistance with institutional approval.

Author Contributions

Mason Marshall - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Isabel Rios - Acquisition of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Guarantor of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2020 Mason Marshall et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.