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Case Report
Invasive micropapillary carcinoma of the breast in male patients: A case report
1 Department of Pathology, Carle Illinois College of Medicine, Carle Foundation Hospital, 611 W. Park Street, Urbana, IL, USA
Address correspondence to:
Ike Uzoaru
MD, Department of Pathology, Carle Foundation Hospital, 611 W. Park St., Urbana, IL 61801,
USA
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Article ID: 100043Z11KC2020
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Cordner K, Uzoaru I. Invasive micropapillary carcinoma of the breast in male patients: A case report. J Case Rep Images Pathol 2020;6:100043Z11KC2020.ABSTRACT
Introduction: Invasive micropapillary carcinoma (IMPC) of the breast is a rare morphologic variant of invasive ductal carcinoma (IDC) and is often associated with poor patient outcomes. Breast cancer is extremely rare in males accounting for approximately 1% of all breast cancers. The most common histologic types include IDC and IMPC. As tumors with IMPC components can be found in other organs, metastatic invasive mammary carcinoma (IMC) should be considered as a differential diagnosis when IMPC is found in the breast.
Case Report: We report a case of primary IMPC of the breast with regional axillary metastasis in an African American male in his eighth decade. A modified radical mastectomy was performed. Upon pathological examination the tumor was positive for estrogen and negative for human epidermal growth factor receptor 2 (HER2). The patient has responded well postoperatively with tamoxifen as the sole treatment.
Conclusion: Due to the rare nature of the disease and the lack of published literature, additional data is needed to better evaluate the response to treatment and survival in male patients with breast IMPC.
Keywords: Invasive ductal carcinoma, Invasive micropapillary carcinoma, Metastatic IMC
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Acknowledgments
The authors acknowledge Patricia G. Stevens, Annette Fudge, and Frances Drone-Silvers for their assistance in preparing the manuscript for submission.
Author ContributionsKeith Cordner - Acquisition of data, Analysis of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Ike Uzoaru - Conception of the work, Design of the work, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2020 Keith Cordner et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
