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Case Report
Neuroblastoma-like schwannoma: An unusual morphologic variant
1 Department of Pathology and Laboratory Medicine, University of Texas Health, 7703 Floyd Curl Drive, MC#7750, San Antonio, Texas, USA
Address correspondence to:
Alia Nazarullah
MD, Assistant Professor/Clinical, Department of Pathology and Laboratory Medicine, University of Texas Health, 7703 Floyd Curl Drive, MC#7750, San Antonio, Texas 78229,
USA
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Article ID: 100049Z11PM2021
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Menon PD, Heim-Hall J, Nazarullah A. Neuroblastoma-like schwannoma: An unusual morphologic variant. J Case Rep Images Pathol 2021;7:100049Z11PM2021.ABSTRACT
Introduction: Neuroblastoma-like schwannoma is a rare morphologic variant of schwannoma with formation of large rosettes.
Case Report: A 29-year-old woman presented with a longstanding left chest wall soft tissue mass. Histology showed small monomorphic tumor cells radially arranged around a fibrocollagenous core forming large rosettes. No evidence of mitotic activity or necrosis was identified. Diffuse S100 reactivity by immunohistochemistry helped confirm the diagnosis as neuroblastoma-like schwannoma.
Conclusion: Awareness of this unusual variant of schwannoma will avoid misinterpretation and confusion with other benign and malignant rosette forming tumors.
Keywords: Neuroblastoma, Rosette, Schwannoma
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Author Contributions
Preethi Dileep Menon - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Josefine Heim-Hall - Analysis of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Alia Nazarullah - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2021 Preethi Dileep Menon et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
