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Case Report
1 Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA
Address correspondence to:
Xi Wang
601 Elmwood Ave., Rochester, NY 14642,
USA
Message to Corresponding Author
Article ID: 100056Z11CM2021
Introduction: The reported incidence of abdominal wall endometriosis (AWE) ranges from 0.03% to 1.08%. A slightly more than 50 cases of abdominal wall endometriosis-associated adenocarcinoma have been reported; commonly clear cell carcinoma, followed by endometrioid adenocarcinoma and serous papillary carcinoma. All of these patients had a history of gynecological or obstetric surgery some time prior to the diagnosis of carcinoma.
Case Report: Here we report a case of a 39-year-old G0P0 female with no history of abdominal/pelvic surgery, who presented with isolated umbilicus endometriosis and an incidental finding of 2 mm adenocarcinoma associated with the endometriosis. Thorough systemic exam was non-eventful, other than a germline variant of the ATM gene of unknown significance.
Conclusion: Our case is unique as it is an isolated sporadic event of malignant transformation of endometriosis, without history of gynecological or obstetric surgery.
Keywords: Abdominal wall endometriosis, Clear cell carcinoma, Endometrioid adenocarcinoma, Malignant transformation of endometriosis
Chelsea Milito - Acquisition of data, Analysis of data, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Xi Wang - Conception of the work, Design of the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
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