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Case Report
Primary amenorrhea due to sclerotic or “non-functional” endometrium: Case presentation and literature review
1 Specialist Obstetrician & Gynaecologist, Department of Obstetrics and Gynaecology, Royal Darwin Hospital, Australia
2 Registrar in Obstetrics & Gynaecology, Department of Obstetrics and Gynaecology, Royal Darwin Hospital, Australia
Address correspondence to:
Nader Gad
PO BOX 41326, Casuarina, NT 0811,
Australia
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Article ID: 100064Z08NG2020
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How to cite this article
Gad N, Yam C, Thomas S. Primary amenorrhea due to sclerotic or “non-functional” endometrium: Case presentation and literature review. J Case Rep Images Obstet Gynecol 2020;6: 100064Z08NG2020.ABSTRACT
Primary amenorrhea is less common than secondary amenorrhea. It can be caused by various anatomical, genetic, or hormonal factors during the development of the reproductive organs. Congenital absence of the endometrium or sclerotic endometrium is a very rare cause of primary amenorrhea with only three cases previously reported in English literature. We describe a case of sclerotic or non-functional endometrium in the context of Mullerian abnormality and normal female karyotype 46 XX.
Keywords: Absent endometrium, Non-functional endometrium, Primary amenorrhea, Sclerotic endometrium
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Author Contributions
Nader Gad - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Chantelle Yam - Conception of the work, Design of the work, Acquisition of data, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Sujatha Thomas - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2020 Nader Gad et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
