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Case Report
Histopathological changes in the prostate after SpaceOAR hydrogel placement
1 Intern, Transitional Year, Madigan Army Medical Center, JBLM, WA, USA
2 Assistant Professor, Department of Pathology, Madigan Army Medical Center, JBLM, WA, USA
3 Assistant Professor, Department of Urology, Madigan Army Medical Center, JBLM, WA, USA
4 Associate Professor, Department of Urology, Madigan Army Medical Center, JBLM, WA, USA
5 Staff, Department of Pathology, Madigan Army Medical Center, JBLM, WA, USA
Address correspondence to:
Kenny Lee
MD, 9040A Jackson Ave, Joint Base Lewis-McChord, WA 98431,
USA
Message to Corresponding Author
Article ID: 100076Z11KL2023
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How to cite this article
Lee K, Cook B, Crisostomo-Wynne T, Speir R, Needs TR. Histopathological changes in the prostate after SpaceOAR hydrogel placement. J Case Rep Images Pathol 2023;9(2):18–21.ABSTRACT
Spacing Organs at Risk (SpaceOAR) hydrogel has been part of the standard protocol in radiation treatment of prostate cancer to minimize radiation damage to the rectum. However, patients may not always follow through with the initial radiation therapy after the placement of the hydrogel due to involvement of the small bowel in the radiation field as seen in our patient. Here, we report the case of a 58-year-old male who underwent robot-assisted laparoscopic prostatectomy two months after SpaceOAR placement, where the prostate specimen was sent to pathology only with clinical history of “prostate cancer.” This case highlights three important points. First, to describe the histopathological changes in a prostatectomy specimen status post-hydrogel placement for radiation treatment of prostate cancer as it is not well-documented. Second, to distinguish the differential diagnoses of granulomatous prostatitis and mucinous adenocarcinoma. And most importantly, to provide complete details with the histopathology requisition form to efficiently correlate histopathologic changes in the appropriate clinical context.
Keywords: Case report, Hydrogel, Prostate cancer, Prostatectomy, SpaceOAR
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Author Contributions
Kenny Lee - Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Benjamin Cook - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Theodore Crisostomo-Wynne - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Ryan Speir - Conception of the work, Design of the work, Acquisition of data, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Todd R Needs - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Kenny Lee et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
