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Case Report
Cylindroma with extensive stromal adipocytic metaplasia likely arising in nevus lipomatosus superficialis: A rare entity
1 Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
2 Libyan International Medical University, Benghazi, Libya
3 Division of Plastic Surgery, McMaster University, Hamilton, Ontario, Canada
4 Department of Pathology and Molecular Medicine, St. Joseph’s Healthcare Hamilton, McMaster University, Hamilton, Ontario, Canada
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Andrea Chen
Department of Pathology and Molecular Medicine, McMaster University, HSC-2N10, 1280 Main Street West, Hamilton, ON L8S 4K1,
Canada
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Article ID: 100098Z11AC2026
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Chen A, Alowami M, Boutross-Tadross O, Cin AD, Alowami S. Cylindroma with extensive stromal adipocytic metaplasia likely arising in nevus lipomatosus superficialis: A rare entity. J Case Rep Images Pathol 2026;12(1):6–9.ABSTRACT
Introduction: Cylindromas are uncommon benign dermal adnexal tumors that tend to arise in the scalp of middle-aged females. Nevus lipomatosus superficialis is a rare hamartomatous connective tissue nevus consisting of mature adipocytes in the reticular dermis.
Case Report: Herein, we report a case of a 53-year-old woman with a congenital scalp lesion demonstrating histopathological features consistent with a benign cylindroma arising within a nevus lipomatosus superficialis.
Conclusion: This case highlights the diagnostic challenge associated with recognizing nevus lipomatosus superficialis in conjunction with other dermal tumors. This is the second reported case of a cylindroma arising from nevus lipomatosus superficialis, in what otherwise would be considered a cylindroma with associated extensive stromal adipocytic metaplasia. The patient’s unique presentation expands the understanding and association of cylindromas with nevus lipomatosus superficialis. Complete surgical excision of the lesion is considered curative treatment, as both entities are benign.
Keywords: Adipocytic metaplasia, Benign adnexal tumors, Cylindroma, Nevus lipomatosus superficialis
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Author ContributionsAndrea Chen - Conception of the work, Design of the work, Acquisition of data, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Moaz Alowami - Conception of the work, Design of the work, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Odette Boutross-Tadross - Conception of the work, Design of the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Arianna Dal Cin - Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Salem Alowami - Conception of the work, Design of the work, Acquisition of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2026 Andrea Chen et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
