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Case Report
Perianal hidradenoma papilliferum in a male: A case report and review of the literature
1 Medical Student, Department of Surgery, Bendigo Health, 100 Barnard Street, Bendigo, Victoria 3550, Australia
2 Pathology Registrar, Anatomical Pathology, Australian Clinical Labs, 1868 Dandenong Road, Clayton, Victoria 3168, Australia
3 General Surgery Registrar, Department of Surgery, Bendigo Health, 100 Barnard Street, Bendigo, Victoria 3550, Australia
4 Pathology Consultant, Anatomical Pathology, Australian Clinical Labs, 100 Barnard Street, Bendigo, Victoria 3550, Australia
Address correspondence to:
Lily Li
Department of Surgery, Bendigo Health, 100 Barnard Street, Bendigo, Victoria,
Australia
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Article ID: 100101Z11LL2026
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Li L, Wong HS, Taylor D, Fernando R. Perianal hidradenoma papilliferum in a male: A case report and review of the literature. J Case Rep Images Pathol 2026;12(1):22–26.ABSTRACT
Introduction: Hidradenoma papilliferum is a rare, benign, predominantly cystic tumor that predominantly affects women between 30 and 60 years of age. It is thought to originate from anogenital mammary-like glands, and therefore most commonly arises in the anogenital region. Clinically, it typically presents as a slow-growing, solitary, circumscribed nodule measuring between 0.5 cm and 2.0 cm in diameter.
Case Report: We report a rare case of a perianal hidradenoma papilliferum in a 70-year-old male who presented with a 2 cm highly pedunculated perianal lesion at the anal verge. This lesion had reportedly been present for several months and had recently increased in size. A literature review was completed and a total of 15 cases of hidradenoma papilliferum were identified in men, of which only three involved the perianal region. The majority of cases (9/15) were located in the head and neck region.
Conclusion: We therefore report a new case of this rare entity. To our knowledge, this is only the fourth documented case of perianal hidradenoma papilliferum in a male patient.
Keywords: Benign tumor, Hidradenoma papilliferum, Papillary hidradenoma, Perianal
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Author Contributions
Lily Li - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Hui Sze Wong - Conception of the work, Design of the work, Acquisition of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Danielle Taylor - Conception of the work, Design of the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Ruchira Fernando - Acquisition of data, Analysis of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2026 Lily Li et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
