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Case Series
Magnetic resonance imaging diagnostic features of giant intracranial tuberculoma
1 Resident Neurosurgery, Department of Neurosurgery, Hamad Medical Corporation, Doha, Qatar
2 Associate Consultant Neurosurgery, Department of Neurosurgery, Hamad Medical Corporation, Doha, Qatar
3 Senior Consultant Neuroradiology, Department of Neuroradiology, Hamad Medical Corporation, Doha, Qatar
4 Associate Professor of Clinical Radiology, Weill Cornell Medicine, Doha, Qatar
Address correspondence to:
Arshad Ali
Department of Neurosurgery, PO Box-3050, Hamad Medical Corporation, Doha,
Qatar
Message to Corresponding Author
Article ID: 101077Z01SS2019
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How to cite this article
Safi SS, Ali A, Vattoth S, Benzabih T. Magnetic resonance imaging diagnostic features of giant intracranial tuberculoma. Int J Case Rep Images 2019;10:101077Z01SS2019.ABSTRACT
Introduction: Central nervous system (CNS) tuberculosis (TB) is among the least common yet most devastating forms of human mycobacterium TB infection. Giant tuberculomas are often confused with brain tumors on cranial magnetic resonance imaging (MRI), emphasizing the need for more meticulous and elaborate imaging analysis.
Case Report: A 38-year-old woman presented with progressive loss of vision associated with headaches. Magnetic resonance imaging of the brain showed a giant left frontal lobe mass lesion with imaging features that could prospectively suggest the diagnosis of tuberculoma. Subsequent operative and histopathological findings confirmed the diagnosis of intracranial tuberculoma.
Conclusion: Parenchymal CNS TB, with or without extracerebral manifestations, may present as a space-occupying lesion with complex neuroimaging morphology suggesting benign or malignant neoplasms. Tuberculomas may be differentiated by their unique MRI pattern, including conventional and advanced MRI sequences like MR spectroscopy (MRS) and MR perfusion (MRP) parameters.
Keywords: Central nervous system, Diagnostic, Giant, Intracranial, Magnetic resonance imaging, Tuberculoma, Tuberculosis
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Author Contributions
Saleh Salah Safi - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Arshad Ali - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Surjith Vattoth - Conception of the work, Design of the work, Acquisition of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Tarek Benzabih - Conception of the work, Design of the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2019 Saleh Salah Safi et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
