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Case Report
1 Department of Neurosurgery, Hamad Medical Corporation, Doha, Qatar
2 Department of Laboratory Medicines and Pathology, Hamad Medical Corporation, Doha, Qatar
Address correspondence to:
Amr El Mohamad
Department of Neurosurgery, Hamad General Hospital, Al Rayyan Road, P.O. Box 3050, Doha,
Qatar
Message to Corresponding Author
Article ID: 101152Z01AM2020
Introduction: Intracranial fungal infection is uncommon condition with high morbidity and mortality. Recently, the incidence has increased owing to the increase of the number of immunocompromised patients (e.g., acquired immunodeficiency syndrome, uncontrolled diabetes mellitus, immunosuppressive drugs, and organ transplant). Furthermore, intracranial fungal granuloma is very uncommon in immunocompetent patients. Unfortunately, it may be masked as it may mimics meningioma clinically and radiologically which may further delay the diagnosis and treatment especially in absence of the risk factors of immunosuppression.
Case Report: We will present a case of intracranial fungal granuloma that mimics olfactory grove meningioma both clinically and radiologically in absence of risk factors of immunosuppression with no paranasal sinuses involvement. In addition to that we will discuss the suspicious radiological signs that might help in making fungal granuloma more possible than meningioma.
Conclusion: Preoperative diagnosis of intracranial fungal granuloma is challenging in immunocompetent patients, in the absence of evidence of nasal infection. There are some radiological clues that could help us to differentiate between fungal granuloma and meningioma preoperatively.
Keywords: Immunocompetent, Intracranial fungal granuloma, Olfactory groove meningioma
Amr El Mohamad - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Mohamad Alhoobi - Acquisition of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Ahmed Eid - Conception of the work, Design of the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Ali Ayyad - Conception of the work, Design of the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Issam Albozom - Conception of the work, Design of the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Firas Hammadi - Conception of the work, Design of the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2020 Amr El Mohamad et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.