Case Series


Could sodium lauryl sulfate be an irritant factor in oral mucosal desquamation?

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1 Department of Oral Medicine, Faculdade de Odontologia, Universidade de São Paulo, São Paulo, Brazil

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Wladimir Gushiken de Campos

Department of Oral Medicine, School of Dentistry, University of São Paulo, Avenida Professor Lineu Prestes, 2227, São Paulo/São Paulo, 05508-001,

Brazil

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Article ID: 101184Z01CE2020

doi: 10.5348/101184Z01CE2020CS

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How to cite this article

Esteves CV, de Campos WG, Paredes WEB, Nunes FD, Alves FA, Lemos CA. Could sodium lauryl sulfate be an irritant factor in oral mucosal desquamation? Int J Case Rep Images 2020;11:101184Z01CE2020.

ABSTRACT


Introduction: Oral mucosal desquamation (OMD) is an irritative reaction caused by products containing sodium lauryl sulfate (SLS), an anionic detergent that causes a stronger denaturation effect in intercellular structure epithelium.

Case Series: Describing four cases of OMD induced by dentifrices, as an endeavor to make the condition better known, improving its diagnosis by clinicians based on minimal intervention.

Conclusion: Oral mucosal desquamation should be considered as a differential diagnosis of the desquamative lesions of the mouth. Clinical signs and symptomatology should disappear in one week after discontinuation potentially involved products.

Keywords: Dentifrice, Detergents, Mouth mucosa, Sodium lauryl sulfate

SUPPORTING INFORMATION


Author Contributions

Camilla Vieira Esteves - Conception of the work, Design of the work, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Wladimir Gushiken de Campos - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Wilber Edison Bernaola Paredes - Conception of the work, Design of the work, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Fabio Daumas Nunes - Analysis of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Fabio Abreu Alves - Conception of the work, Design of the work, Analysis of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Celso Augusto Lemos - Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Guarantor of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2020 Camilla Vieira Esteves et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.