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Case Report
Optic neuritis in post-Covid rhino-orbito-cerebral mucormycosis (ROCM): A rare presentation
1 DOMS, DNB Ophthalmology, Assistant Professor, Dept. of Ophthalmology, GSVM Medical College and LLR Hospital, Kanpur, U.P., India
2 MS Ophthalmology, Professor and HOD, Dept. of Ophthalmology, GSVM Medical College and LLR Hospital, Kanpur, U.P., India
3 MS, Junior Resident, MS Ophthalmology, GSVM Medical College and LLR Hospital, Kanpur, U.P., India
4 MS Ophthalmology, Assistant Professor, GSVM Medical College and LLR Hospital, Kanpur, U.P., India
5 Senior Resident, MS Ophthalmology, GSVM Medical college and LLR Hospital, Kanpur, U.P., India
6 Junior Resident, MS Ophthalmology, GSVM Medical College and LLR Hospital, Kanpur, U.P., India
Address correspondence to:
Anshika Gupta
Room No- 4, PG Girls Hostel, GSVM Medical College, Kanpur, U.P.,
India
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Article ID: 101256Z01PS2021
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How to cite this article
Singh P, Khan P, Gupta A, Patel N, Chandra T, Yadav DK. Optic neuritis in post-Covid rhino-orbito-cerebral mucormycosis (ROCM): A rare presentation. Int J Case Rep Images 2021;12:101256Z01PS2021.ABSTRACT
Introduction: Rhino-orbito-cerebral mucormycosis is a devastating opportunistic and fulminant infection. We report an unusual and rare case of optic neuritis as the complication of post-Covid rhino-orbito-cerebral mucormycosis (ROCM).
Case Report: A 37-year-old patient presented with ocular symptoms associated with ROCM and diminution of vision in left eye 14 days post-Covid. Radiological investigation (magnetic resonance imaging, MRI) showed heterogeneous altered signal intensity in left optic nerve. Fundus examination showed characteristic findings of optic neuritis.
Conclusion: In advanced stage of sino-invasive rhino-orbito-cerebral mucormycosis perineural invasion is a proven histological feature. In our case scenario, the optic nerve of the patient got involved through perineural spread of mucormycosis, causing inflammation along the nerve resulting in optic neuritis.
Keywords: Optic neuritis, Perineural invasion, ROCM
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Author Contributions
Parul Singh - Conception of the work, Design of the work, Analysis of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Perwez Khan - Conception of the work, Design of the work, Analysis of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Anshika Gupta - Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Namrata Patel - Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Tejasvini Chandra - Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Dinesh Kumar Yadav - Acquisition of data, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2021 Parul Singh et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
