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Case Report
Myocardial amyloidosis combined with atrial giant thrombosis secondary to multiple myeloma: A case report
1 Cardiovascular Disease Center, Central Hospital of Tujia and Miao Autonomous Prefecture, Hubei University of Medicine, Shiyan, Hubei Province 442000, China
2 Department of Pathology, Central Hospital of Tujia and Miao Autonomous Prefecture, Enshi Clinical College of Wuhan University, Enshi Prefecture, Hubei Province 445000, China
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Yuanhong Li
Cardiovascular Disease Center, Central Hospital of Tujia and Miao Autonomous Prefecture, Enshi Prefecture, Hubei Province 445000,
China
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Article ID: 101317Z01JZ2022
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Zhao J, Ni Z, Luo Y, Huang R, Su K, Li Y. Myocardial amyloidosis combined with atrial giant thrombosis secondary to multiple myeloma: A case report. Int J Case Rep Images 2022;13(2):5–9.ABSTRACT
Introduction: Multiple myeloma (MM) is a hematologic disorder that is relatively common in the elderly population. Given the rapid development, limited survival, and poor prognosis of the majority of patients, a definitive, prompt diagnosis is critical for treating individuals with multiple myeloma accompanied with cardiac amyloidosis. The incidence of myocardial amyloidosis with MM, relatively speaking, is low and early clinical manifestations are nonspecific. Atrial thrombi, with low detection, are a hallmark of poor prognosis of patients diagnosed MM with amyloidosis cardiomyopathy.
Case Report: Aiming to serve as useful feedback information for judging the prognosis of target patient, we now analyzed the clinical data of an elderly female with atrial thrombi as the main symptom and impaired cardiac function combined with echocardiography electrocardiography (ECG), laboratory data, cell Congo Red staining and other manifestations to diagnose amyloidosis combined with MM.
Conclusion: The formation of atrial thrombi is closely related to the prognosis of myocardial amyloidosis and in order to identify atrial thrombi early and to intervene early, transesophageal ultrasound should be included as part of routine investigations in patients with myocardial amyloidosis.
Keywords: Atrial thrombi, Echocardiography (ECG), Multiple myeloma (MM), Myocardial amyloidosis
SUPPORTING INFORMATION
Acknowledgments
This work was supported by the Effect of Selective Renal Artery Sympathetic Ablation on Ventricular Arrhythmia after Myocardial Infarction (No. WJ2015MA021).
Author ContributionsJingbo Zhao - Conception of the work, Design of the work, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Zhu Ni - Acquisition of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Yinhua Luo - Acquisition of data, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Rui Huang - Acquisition of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Ke Su - Acquisition of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Yuanhong Li - Conception of the work, Design of the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2022 Jingbo Zhao et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
