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Case Report
Transverse myelitis after immunization against SARS-CoV-2: A case report
1 Medical student at Iguaçu University - UNIG/RJ, Nova Iguaçu - RJ, Brazil
2 Physician, Neurologist, Adjunct Professor of Medicine at Universidade Iguaçu, Iguaçu University - UNIG/Nova Iguaçu, RJ, Brazil
3 Professor of Neurology - Universidade Iguaçu - UNIG-RJ, Nova Iguaçu - RJ; Physician of the Neurology Service of Nova Iguaçu General Hospital, Nova Iguaçu, RJ, Brazil
4 Department of Neurology of Hospital Geral de Nova Iguaçu, Adjunct Professor of Medicine at Iguaçu University - UNIG/Nova Iguaçu, RJ, Brazil
Address correspondence to:
Antônio Marcos da Silva Catharino
Rua Gavião Peixoto 70, Room 811, CEP 24.2230-100, Icaraí, Niterói-RJ,
Brazil
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Article ID: 101404Z01DP2023
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Pereira DA, Leme LE, Dantas SAB, Neves MAO, Canedo GM Jr, da Silva Catharino AM. Transverse myelitis after immunization against SARS-CoV-2: A case report. Int J Case Rep Images 2023;14(2):21–25.ABSTRACT
Introduction: Transverse myelitis (TM) is a clinical syndrome of varied etiology, one of its causes being the immune-mediated lesion caused by the COVID-19 vaccine. It causes sensory, motor, and autonomic dysfunctions that can be bilateral, unilateral, or asymmetrical and that can change rapidly. The clinical presentation of TM is mainly represented by bilateral weakening of the lower limbs (LL), but it varies depending on the level of the spinal cord involved. Early diagnosis and treatment can benefit recovery and prevent a recurrence.
Case Report: We report the case of a 50-year-old man, an engineer by profession, who reported that in the second dose of immunization against SARS-CoV-2, he began to have a tingling sensation (dysesthesia) in the lower limbs. After four months, between the second and third doses, about five months, a new clinical picture of paresis had erupted, associated with tactile, thermal, and painful hypoesthesia.
Conclusion: Due to the significant impact of COVID-19 on health, especially about neurological impacts, disorders associated with the vaccine should always be considered when approaching patients after vaccination. Post-vaccination TM, as it has a difficult diagnosis (excluding other causes) and a variable prognosis (from total recovery without damage to complete paraplegia, respiratory failure, or upper cervical injury), establishing its diagnosis in an early diagnosis is essential for a better prognosis.
Keywords: COVID-19, Transverse myelitis, Vaccine
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Acknowledgments
The authors acknowledge the individuals here who contributed to the work but do not qualify for authorship.
Author ContributionsDaniel Antunes Pereira - Conception of the work, Design of the work, Analysis of data, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Luiza Eyer Leme - Conception of the work, Design of the work, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Shara Aline Bueno Dantas - Conception of the work, Design of the work, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Marco Antônio Orsini Neves - Conception of the work, Design of the work, Acquisition of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Gilberto Canedo M Jr - Conception of the work, Design of the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Antônio Marcos da Silva Catharino - Conception of the work, Design of the work, Analysis of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Daniel Antunes Pereira et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
