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Case Report
Fatal spontaneous intraperitoneal hemorrhage in association with apixaban: A case report
1 MRCS, SHO, Department of Trauma and Orthopaedic Surgery, University Hospital Waterford, Dunmore Road, Waterford X91 ER8E, Ireland
2 FRCS, SpR, Department of Trauma and Orthopaedic Surgery, University Hospital Waterford, Dunmore Road, Waterford X91 ER8E, Ireland
3 FRCS, Consultant, Department of Trauma and Orthopaedic Surgery, University Hospital Waterford, Dunmore Road, Waterford X91 ER8E, Ireland
Address correspondence to:
Daniel P Mckenna
Department of Trauma and Orthopaedic Surgery, University Hospital Waterford, Dunmore Road, Waterford X91 ER8E,
Ireland
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Article ID: 101455Z01DM2024
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How to cite this article
Mckenna DP, Kelly M, Murphy T. Fatal spontaneous intraperitoneal hemorrhage in association with apixaban: A case report. Int J Case Rep Images 2024;15(1):99–102.ABSTRACT
We present the case of an 80-year-old gentleman with a spontaneous intraperitoneal hemorrhage secondary to direct oral anticoagulant (DOAC) medication. As far as we are aware this is the third documented case of spontaneous intraperitoneal hemorrhage in association with direct oral anticoagulants (DOACs) therapy. Previously published cases have also cited apixaban as the associated DOAC. With their increasing prevalence, spontaneous intraperitoneal hemorrhage should be a recognized presentation for the patient in extremis on DOAC therapy.
Keywords: Apixaban, Hemorrhage, Intraperitoneal, Spontaneous
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Author Contributions
Daniel P Mckenna - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Martin Kelly - Conception of the work, Design of the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Terence Murphy - Conception of the work, Design of the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2024 Daniel P Mckenna et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
