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Case Report
Metaplastic breast cancer: A case report and literature review
1 College of Arts and Sciences, The Ohio State University, Columbus, OH 43210, USA
2 Department of Pathology, University of Toledo Medical Center, 3000 Arlington Avenue, Toledo, OH 43614, USA
Address correspondence to:
Dalia Y Ibrahim
Department of Pathology, University of Toledo Medical Center, Toledo, OH 43614,
USA
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Article ID: 100069Z11LO2023
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Osman L, Ibrahim DY. Metaplastic breast cancer: A case report and literature review. J Case Rep Images Pathol 2023;9(1):12–16.ABSTRACT
Introduction: Breast cancer is the second most common cancer among women in the United States. Metaplastic breast cancer is characterized by two or more poorly differentiated cellular types, with epithelial or mesenchymal components. Metaplastic breast carcinoma is a rare and aggressive entity, accounting for less than 1% of invasive breast cancers. Hence, there is insignificant literature and research. Few cases are described in the literature. We report a rare case of metaplastic breast carcinoma with squamous and spindle cell differentiation.
Case Report: An 82-year-old female was diagnosed with metaplastic breast cancer with squamous and spindled differentiation based on histological appearance. She underwent mastectomy, and we track her radiation follow-up.
Conclusion: The report reviews and corroborates existing literature regarding clinical features, histologic characteristics, and treatment methods, and explores genetic components and clinical trials underway.
Keywords: Breast cancer, Metaplastic carcinoma, Triple negative
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Author Contributions
Lojayne Osman - Analysis of data, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Dalia Y Ibrahim - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Lojayne Osman et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
